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Disease and Illnesses

Ötzi the Iceman is housed at the South Tyrol Museum of Archaeology, where conservationists periodically humidify his remains.

Ötzi the Iceman May Have Carried a Cancer-Causing Strain of HPV, a Common Virus Still Plaguing Humans Today

A new study, which also found evidence of the high-risk strain in 45,000-year-old remains, suggests HPV has evolved alongside humans for many millennia

Naked mole-rats are unusual for their long lives and resistance to cancer. Now, researchers suggest the rodents not only tolerate but prefer to be in low-oxygen air.

Naked Mole-Rats Prefer Low-Oxygen Air That Would Kill Most Mammals, Adding to Their List of Death-Defying Superpowers

These underground rodents are the first mammals found to actively choose air with lower-than-normal oxygen levels. Their remarkable ability to survive these conditions could offer a key model for researchers studying new treatments for stroke or lung diseases in humans

Researchers investigated the associations between preservatives and the risk of developing cancer and type 2 diabetes.

Eating Large Amounts of Certain Preservatives Might Increase Your Risk of Developing Cancer and Type 2 Diabetes

Two studies tracked more than 100,000 participants over 14 years to reveal the trends. But they can’t confirm a direct link between eating these preservatives and developing disease, especially because some of the additives were eaten in foods that contain known carcinogens

Many public health experts, immunologists and pediatricians criticized the revised childhood vaccine schedule, arguing that the changes will likely lead to more disease outbreaks.

U.S. Overhauls Immunization Schedule for Kids, Removing Recommendations for Vaccines Against the Flu, RSV and More

Announced on Monday, the revised schedule drops the number of recommended immunizations from 17 to 11. The CDC suggests that only “high-risk” kids should get many of the vaccines that are no longer endorsed

A humpback whale off the coast of Iceland

By Collecting Whale Breath, Researchers Detected a Deadly Virus in the Arctic for the First Time

Flying a drone with Petri dishes above exhaling whales helped scientists identify a dangerous pathogen that can damage the animals’ respiratory, immune and nervous systems

Estrogen may cause certain colon cells, shown in green in this microscope image, to release a hormone called peptide YY. This, in turn, causes a different type of colon cell, colored magenta, to pump out the chemical messenger serotonin, which activates pain-sensing nerve fibers.

Women Are More Likely to Have Irritable Bowel Syndrome. This Newfound Gut Pain Pathway Might Explain Why

The hormone estrogen—which female animals typically have more of than males—triggers a molecular cascade in the gut that leads to pain signals, a study in mice suggests

Nanoflowers, which look white, can help healthy cells, colored yellow, deliver mitochondria, colored red, to nearby cells. 

A New Way to Boost the Powerhouses of the Cell Might Combat Aging and Degenerative Diseases, Lab Study Suggests

Creating mini mitochondria factories helped recharge damaged cells in a dish, providing proof-of-concept work that could pave the way to new regenerative medicine therapies

In 2025, researchers watched an interstellar comet, learned about human origins and traced the spread of measles.

The Ten Most Significant Science Stories of 2025, From Medical Breakthroughs to an Interstellar Visitor

All year long, these moments captivated the public, demonstrated dangerous trends, and pushed research and innovation forward

Illustration of a T lymphocyte white blood cell, depicted in blue, attacking a cancer cell, shown in red

Scientists Engineered Cancer-Fighting Cells Inside Patients’ Bodies—and Two Early Trials Show Promise

Two recent studies show the novel therapy works in people with multiple myeloma, but researchers are trying to minimize side effects

The Black Death may have killed more than half of Europe's population within just a few years.

A Volcanic Eruption in 1345 May Have Triggered a Chain of Events That Brought the Black Death to Europe

Ash from the explosion may have led to crop failure and famine in southern Europe, leading some Italian cities to import grain—which possibly carried fleas infected with the bubonic plague

A microscope image of HIV particles, in red, replicating from an infected cell, in blue.

A New Trial Put Immune System-Boosting Therapies to the Test to Fight HIV, Raising Hopes for Keeping the Virus at Bay

In the small study, seven out of ten participants maintained low levels of HIV for several months after receiving the experimental treatment and stopping their usual daily medications

The World Health Organization conditionally recommends the use of GLP-1 drugs, including tirzepatide, marketed as Mounjaro and Zepbound, for obesity treatment. 

Here’s What the World Health Organization Had to Say About GLP-1s in its First-Ever Guideline on the Drugs

The health agency supports the long-term use of the medications in combination with a healthy diet and exercise, and calls for equitable access to the drugs

Smithsonian magazine's picks for the best books about science in 2025 include Replaceable You, Dinner With King Tut and North to the Future.

The Best Books of 2025

The Ten Best Science Books of 2025

From “experimental archaeology” to the mysterious appeal of exploration, the wide-ranging subjects detailed in these titles captivated Smithsonian magazine’s science contributors this year

A digital illustration of an HIV-infected T cell. Once infected, the immune cell is hijacked by the virus to produce and release many new viral particles before dying. As more T cells are destroyed, the immune system is progressively weakened.

New Trials Hint That ‘Functional Cure’ for HIV May Be Within Reach, Helping Some Patients Achieve Lasting Remission

People infected with HIV must take antiretroviral drugs for life. But engineered antibodies appeared to suppress the virus for certain participants in recent trials in Africa and Europe

Oliver and his father, Ricky

This Toddler Was the First Person to Receive a Test Treatment for a Rare Genetic Disorder. Nine Months Later, His Progress Is Inspiring Hope

Oliver Chu is one of five kids participating in a clinical trial investigating a gene therapy for Hunter syndrome, a disorder with symptoms akin to childhood dementia that limits life expectancy

Researchers have developed a promising new antivenom effective against more than a dozen venemous snake species, according to trials in mice.

Researchers Create a New Antivenom That Can Combat Bites From 17 Snake Species, Trials in Mice Suggest

Snakebites are among the deadliest neglected tropical diseases, and scientists have long been searching for more effective ways to prevent their devastating effects

Thousands of men died as Napoleon's army retreated from Russia in 1812.

Cold, Hungry and Thirsty, Napoleon’s Troops Also Suffered From Several Diseases as They Retreated From Russia

New research finds evidence of two previously undocumented infections that likely plagued the French emperor’s Grande Armée during the retreat from Moscow

Nobel Committee Secretary-General Thomas Perlmann addresses journalists during an October 6 press conference announcing the 2025 Nobel Prize in Physiology or Medicine in Stockholm, Sweden.

Trio of Researchers Awarded Nobel Prize for Groundbreaking Discovery of Immune Cells That Prevent Autoimmune Disease

Mary Brunkow, Fred Ramsdell and Shimon Sakaguchi’s research revealed a new class of cells shaking up scientists’ understanding of the human immune system

Huntington's disease gradually damages the caudate nucleus, pictured in red. 

Experimental Gene Therapy Successfully Treats Huntington’s Disease for the First Time

Preliminary results from a small study offer hope for treatment of the degenerative disease

“Brain rot” was the Oxford Word of the Year 2024.

Can You Really ‘Rot’ Your Brain by Scrolling Too Much on Your Smartphone?

While that message has been spread on social media, researchers are just beginning to understand how the devices affect the mind

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