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Innovations

Easy-Bake Oven, 1977

How the Easy-Bake Oven, an Appliance That Allowed Kids to Heat Treats With a Light Bulb, Revolutionized the Toy Industry

The product, launched in 1963, became a staple in American households

Surgeons removed the patient's failing lungs and temporarily replaced them with an artificial version, saving his life.

Artificial Lungs Kept a Dying Man Alive For 48 Hours—Until He Was Well Enough to Receive an Organ Transplant

The patient is faring well nearly three years later, thanks to the life-saving device

A historic marker at Jackson State University, ca. 1950, from the “At the Vanguard” exhibition at the National Museum of African American History and Culture

How Historically Black Schools Create and Preserve Their Own History Through Amazing Artifacts, From Paintings to Marching Band Hats

For nearly 200 years, HBCUs have educated Black Americans. Now, a new exhibition highlights special objects from five universities

A six-fingered version of the robotic hand

This Detachable Robotic Hand Can Scurry Around and Grasp Objects Just Like Thing From the Addams Family

With up to six fingers that can bend in multiple directions, the innovative tool could one day be used to carry out tasks in tight spaces

Through gene-editing, researchers in the field of synthetic biology hope to make endangered species more resilient against disease or climate change and protect human health, among other goals.

Three Stunning Ways Biologists Aim to Edit Animal and Plant Genes to Fight Diseases and Extinction

The strategy, known as synthetic biology, is gaining momentum globally as a conservation tool and human health solution, despite attracting some critics

Naked mole-rats are unusual for their long lives and resistance to cancer. Now, researchers suggest the rodents not only tolerate but prefer to be in low-oxygen air.

Naked Mole-Rats Prefer Low-Oxygen Air That Would Kill Most Mammals, Adding to Their List of Death-Defying Superpowers

These underground rodents are the first mammals found to actively choose air with lower-than-normal oxygen levels. Their remarkable ability to survive these conditions could offer a key model for researchers studying new treatments for stroke or lung diseases in humans

Research suggests that elephants use certain plants for medicinal purposes.

When Some Elephants Raid Farms, They Might Not Be After a Snack. They Could Be Looking for Medicinal Plants

A recent study suggests that the large mammals may seek out parts of bananas and papayas when they’re suffering from gut parasites, sparking a cross-species exchange of pharmaceutical knowledge

Nanoflowers, which look white, can help healthy cells, colored yellow, deliver mitochondria, colored red, to nearby cells. 

A New Way to Boost the Powerhouses of the Cell Might Combat Aging and Degenerative Diseases, Lab Study Suggests

Creating mini mitochondria factories helped recharge damaged cells in a dish, providing proof-of-concept work that could pave the way to new regenerative medicine therapies

A rinkhals (Hemachatus haemachatus) in Hluhluwe, South Africa, performs a threat display. These snakes tend to live on the edges of human communities.

The High-Stakes Quest to Make Snakebites Survivable Took Leaps Forward This Year, With Promising New Avenues to Safer Antivenoms

A wave of fresh science is challenging a century-old treatment and offering hope to the people snakebites harm most—often far from hospitals and help

A 1984 front-loading Betamax video recorder

This Revolutionary but Largely Forgotten Video Recorder Debuted 50 Years Ago. Devoted Fans Say the Machine Had the Best Quality of Its Time

Tech lovers continue to tout the superior resolution of Sony’s Betamax—even though it became obsolete after VHS overtook it

Smithsonian magazine's picks for the best books about science in 2025 include Replaceable You, Dinner With King Tut and North to the Future.

The Best Books of 2025

The Ten Best Science Books of 2025

From “experimental archaeology” to the mysterious appeal of exploration, the wide-ranging subjects detailed in these titles captivated Smithsonian magazine’s science contributors this year

A digital illustration of an HIV-infected T cell. Once infected, the immune cell is hijacked by the virus to produce and release many new viral particles before dying. As more T cells are destroyed, the immune system is progressively weakened.

New Trials Hint That ‘Functional Cure’ for HIV May Be Within Reach, Helping Some Patients Achieve Lasting Remission

People infected with HIV must take antiretroviral drugs for life. But engineered antibodies appeared to suppress the virus for certain participants in recent trials in Africa and Europe

Students learn anatomy from an Asclepius AI Table, which merges interactive elements and artificial intelligence.

Medical Students Are Learning Anatomy From Digital Cadavers. Can Technology Ever Replace Real Human Bodies?

From interactive diagrams to A.I. assistants, virtual tools are beginning to supplant physical dissections in some classrooms

Researchers have developed a promising new antivenom effective against more than a dozen venemous snake species, according to trials in mice.

Researchers Create a New Antivenom That Can Combat Bites From 17 Snake Species, Trials in Mice Suggest

Snakebites are among the deadliest neglected tropical diseases, and scientists have long been searching for more effective ways to prevent their devastating effects

Tim Andrews and his wife leave the hospital after he received the pig kidney transplant about nine months ago.

Pig Kidney Transplant Removed From Patient After a Record-Breaking 271 Days

Tim Andrews was the fourth patient in the United States to receive a pig kidney transplant. He will now return to dialysis and wait for a kidney from a human donor

Horseshoe crabs evolved 445 million years ago and have been around for 1,500 times longer than Homo sapiens. It was not until the 20th century, however, that scientists discovered life-saving properties in their blood.

Horseshoe Crab Blood Has Long Helped Us Make Safe Medicines. Now, Alternatives That Spare the Ancient Creatures Might Be Breaking Through

An enzyme in the blue blood has been key to testing vaccines since the 1980s, raising concerns for the crabs’ population. But regulatory approval and new data are signaling the tide may be turning

Participants received retinal implants that restored some of their vision. 

Electronic Eye Implant Restored Vision in Patients With Age-Related Macular Degeneration

The device could be a boon for millions with vision loss from advancing age

An aerial view of Altadena on March 11, 2025, shows surviving trees and new greenery amid homes destroyed in the Eaton Fire.

After the L.A. Fires, Locals Turn to Native Plants to Help Shield Homes From Flames and Clean Contaminated Soil

Scientists and community members in Altadena are testing ways that California species can assist efforts to rebuild

Hematoids can shed light on blood formation during early human development.

Researchers Created Structures That Produced Blood Cells in the Lab—With a Process That Mimics Real Human Embryos

The advance could carry significant implications for studying blood diseases and early human development

The mold growing on batches of Bayley Hazen Blue cheese changed from green to white between 2016 and the present day.

Scientists Watch Fungi Evolve in Real Time, Thanks to a Marriage Proposal in a Cheese Cave

A new study pinpoints a disruption in a gene that made a beloved blue cheese’s rind go from green to white

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