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At Indiana University, a team of scientists used this Roche 454 to sequence the 350 million base pairs of Theobroma cacao, the plant that gives us chocolate.

The World of Chocolate

The Big, Refrigerator-Sized Machine That Saved Chocolate

When cacao production was threatened by disease, the Mars candy company launched a global initiative to sequence the plant’s genome

The male panda cub (upper right) is now 4.9 ounces, having gained almost a full ounce in the last 72 hours. The cub was sired by Tian Tian by artificial insemination.

It’s a Boy! The Panda Cub Was Fathered by the National Zoo’s Tian Tian (Video)

Zoo scientists say that their newly developed genetic test determined the sex of the panda

"Home of a Rebel Sharpshooter." A soldier finds his final resting place, July 1863.

Why Can’t We Turn Our Eyes Away From the Grotesque and Macabre?

Alexander Gardner’s photographs of Civil War corpses were among the first to play to the uncomfortable attraction humans have for shocking images

Does this look infected?

Life May Have Spread Through the Galaxy Like a Plague

If alien life is distributed in a pattern that mirrors epidemics, it could be strong support for the theory of panspermia

The smaller of the two twin panda cubs has died.

Updated: One of the National Zoo’s Panda Cubs Has Died

The Zoo announced on August 26 that the smaller of its newborn twin panda cubs has died

Don Herbert was "Mr. Wizard," an educator who loved spectacle as much as he loved science.

Meet Mr. Wizard, Television’s Original Science Guy

In the 1950s and 1960s, Don Herbert broadcast some of the most mesmerizing, and kooky, science experiments from his garage

On August 29, 1985, Michael Drummond became the sixth person, and the youngest, to be implanted with an artificial heart.

The Innovative Spirit

Thirty Years Ago, an Artificial Heart Helped Save a Grocery Store Manager

The Smithsonian, home to the Jarvik 7 and a host of modern chest-pumping technologies, has a lot of (artificial) heart

The smallest cub, which weighed just 86 grams at birth, is seen here being hand-reared with bottle formula feedings.

Panda Update: Giant Panda Mom Mei Xiang Won’t Exchange Care of Cubs

Smaller cub is receiving infant formula and fluids from Zoo veterinarians

Ask Smithsonian 2017

What Happens to Spiders That Get Sucked Into a Vacuum?

You asked, we answered

The Broken Promise of the Levees That Failed New Orleans

A piece of concrete serves as a reminder of how Hurricane Katrina shattered a city’s faith

Mei Xiang delivers twins, a historic record—only the third time in the United States.

A Second Panda Cub is Born at the Zoo (New Pictures)

After giving birth to one cub, the Zoo’s 17-year-old female panda, hours later, delivers a second cub

Screen grab from Panda Cam

BREAKING: A Panda Cub is Born at the National Zoo (Video)

The 17-year-old female giant panda Mei Xiang gives birth

Ask Smithsonian

Ask Smithsonian: Why Do Flamingos Stand on One Leg?

Flamingos may be doing their one-legged tree pose to stay warm or just because it’s comfortable

Veterinarians detected what they believe is a developing giant panda fetus in an ultrasound procedure on giant panda Mei Xiang. Based on the size of the fetus, which is about four centimeters, officials say that Mei Xiang could give birth early next week, or possibly in early September.

Panda Cub (Or Is It Bamboo?) Detected in Mei Xiang’s Ultrasound

Breeding pandas is complicated and frustrating. The Zoo’s female Giant Panda has delivered two healthy cubs in the past ten years

Visitors apply aerodynamic principles to design their own virtual fighter jets and then race against other in a high-speed flying competition.

A Next Gen Museum Show Takes Aim at Inspiring Next Gen Ingenuity

Curators are betting high-tech playtime will turn today’s kids into tomorrow’s engineering visionaries

Many foodies and soda lovers swear there’s a discernible difference between Coke made with sugar and Coke made with high-fructose corn syrup—a truer, less “chemical-y” taste; a realer real thing.

The Innovative Spirit

The Story of Mexican Coke Is a Lot More Complex Than Hipsters Would Like to Admit

A nasty trade war and questionable scientific assumptions make it difficult to discern what is, and what isn’t, the real thing

The Innovative Spirit

When a Trip to the Zoo Resulted in an Engineering Breakthrough

Megan Leftwich, an engineering professor at George Washington University, is building a robotic flipper based on her observations of sea lions

A hyalotype photo printed and mounted as a glass lantern slide, by William and Frederick Langenheim.

Cool Finds

This is the First Known Photo of the Smithsonian Castle

On the Smithsonian’s 175th birthday, a glimpse into the iconic Castle’s construction

Robert Frost by Clara Sipprell, gelatin silver print, 1955.

Poetry Matters

What Gives Robert Frost’s “The Road Not Taken” Its Power?

A Smithsonian poet examines its message and how it encapsulates what its author was all about

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