More than 40 variations are played around the world today, although the core tiles and the way the tiles are shuffled and stacked to begin the game remain the same.

The Asian Game of Mahjong, Which Creates Order Out of Chaos, Is Trending in the West

The 200-year-old tile game is popping up in clubs, hotels and parties as a way for Gen Zers and millennials to connect

The world’s first Covid-19 human challenge study was born in early 2021.

What Have We Learned From Intentionally Infecting People With Covid-19?

Challenge trials help researchers study immune responses. Skeptics still doubt the approach is worth the risks

The U.S. has reported 66 human cases of H5N1 bird flu since March 2024, but a recent death of a Louisiana resident marks the country’s first fatality from the virus.

Officials Report the First Human Death From Bird Flu in the U.S. Here’s What to Know About the Virus

The death of a Louisiana resident who was over the age of 65 signals that future H5N1 infections are not guaranteed to be mild, health experts say

DNA on Earth is built from sugars with a property known as right-handedness. Though left-handed sugars aren't used by any known life, scientists can create them—but now, researchers say they shouldn't.

Scientists Warn of an ‘Unprecedented Risk’ From Synthetic ‘Mirror Life,’ Built With a Reverse Version of Natural Proteins and Sugars

So-called mirror cells could rampage through our ecosystems, food supply and immune systems, experts say, potentially without existing barriers to protect against them

The new adaptation of The Decameron is “like a medieval ‘Love Island,’ and it descends into Lord of the Flies chaos,” says actor Tanya Reynolds.

Based on a True Story

The Real Story Behind Netflix’s ‘The Decameron’

Loosely based on Giovanni Boccaccio’s 14th-century collection of short stories, the series follows a group of Italian nobles and servants who flee to the countryside to escape the Black Death

A new study sheds light on the timeline of the human immune response when confronted with SARS-CoV-2 and other infectious diseases.

Why Are Some People Seemingly Immune to Covid-19? Scientists May Now Have an Answer

Researchers tracked the immune responses of 16 people intentionally exposed to SARS-CoV-2 and pinpointed a gene that seems to help resist the virus before it can take hold

The Black Death killed tens of millions of people in the mid-1300s, but scientists and historians are still trying to figure out how it spread.

Did Body Lice Spread Bubonic Plague? Research Suggests the Parasites Are Better Vectors Than Thought

These blood-sucking insects are capable of transmitting the bacteria that caused the Black Death, according to a laboratory study

Human-caused biodiversity loss is a major factor that could contribute to more frequent and severe disease outbreaks, according to a new study.

Biodiversity Loss Increases the Risk of Disease Outbreaks, Analysis Suggests

Researchers found that human-caused environmental changes are driving the severity and prevalence of disease, putting people, animals and plants at risk

Hand washing is one of the simplest ways to prevent disease transmission.

The Dirty Secret About How Our Hands Spread Disease

The human hand is an incredible tool—and a deadly threat

The novel is set during the early days of the pandemic, when New Yorkers applauded from their windows each night for medical staff and essential workers.

36 Famous Authors Co-Wrote a Pandemic Novel. Can You Guess Who Drafted Each Section?

Margaret Atwood, R.L. Stine and John Grisham are among the writers who collaborated on “Fourteen Days,” which follows a group of New Yorkers who gather on a Manhattan rooftop to swap stories beginning in March 2020

The proposed changes to isolation guidelines would bring the CDC's approach to Covid-19 closer to California's and Oregon's. Both states amended their isolation guidance within the last year.

CDC Considers Dropping Five-Day Covid Isolation Guideline

While no official decision has been made, symptomatic patients might be able to stop isolating if they are fever-free for 24 hours and are beginning to feel better under the proposed change

Researchers studied climate fluctuations in Roman Italy between 200 B.C.E. and 600 C.E.

New Research

Plagues That Ravaged the Roman Empire Were Linked to Periods of Cold Weather

The changing climate may have had ripple effects that made people more susceptible to disease, new research suggests

People with long Covid sit in the audience at a U.S. Senate hearing about the condition on January 18.

Scientists Find Indicators in Blood Linked to Long Covid, Hinting at Future Treatments

One part of the immune system appeared to be overly active in long Covid patients in a small study, a finding researchers hope could help diagnose or treat the condition

Covid-19 lockdowns had all kinds of effects on wild populations, helping some and hindering others. In one Mexican marine park, though, the sudden lack of tourists led to an increase in the density and diversity of marine species.

During Covid-19 Lockdowns, Fish Flourished in This Park

In the absence of tourists, the animals increased within Mexico’s Cabo Pulmo National Park

In 2022, nearly 46 percent of health workers felt burnt out either often or very often.

Health Care Workers Are Burning Out, CDC Says

Depression, anxiety and harassment of health professionals have risen beyond crisis levels, per a new report from the agency

Patients with the 1918 flu at a barracks hospital in Colorado.

The 1918 Flu Hit Frailer People the Hardest, Study Suggests

Skeletons of people who died before and during the 20th-century pandemic counter the narrative that young and healthy people were targeted by the disease

A new round of Covid-19 vaccinations was recommended by Centers for Disease Control and Prevention advisers on Tuesday.

What to Know About the New Covid-19 Vaccines, Now Recommended by CDC Advisers

Experts say the latest boosters are effective against emerging variants including EG.5.1 and BA.2.86

Covid-19 cases are on the rise in the U.S., but experts say it is not unexpected.

Covid-19 Hospitalizations Show an Uptick in the U.S. but Remain Low

Since the end of the nation’s public health emergency for the virus, hospitalizations are one of the best available indicators of trends in case totals

Candida auris

This Fungus Is Quickly Spreading, and Climate Change May Be to Blame

Washington state reported its first case of Candida auris, which can cause illness in people with weakened immune systems

A woman with long Covid, suffering symptoms including extreme fatigue and brain fog, rests on her couch on February 3, 2022.

Long Covid’s Brain Fog Is Akin to ‘Aging Ten Years,’ Study Finds

Scientists tested the cognitive function of more than 3,000 participants and found those with longer-lasting Covid symptoms had the strongest decline

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