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Health

Estrogen may cause certain colon cells, shown in green in this microscope image, to release a hormone called peptide YY. This, in turn, causes a different type of colon cell, colored magenta, to pump out the chemical messenger serotonin, which activates pain-sensing nerve fibers.

Women Are More Likely to Have Irritable Bowel Syndrome. This Newfound Gut Pain Pathway Might Explain Why

The hormone estrogen—which female animals typically have more of than males—triggers a molecular cascade in the gut that leads to pain signals, a study in mice suggests

New research suggests that swearing boosts physical performance by reducing inhibitions.

Need a Quick Boost in Physical Strength? Try Blurting Out Some Curse Words, a Study Suggests

When repeating four-letter words, participants held a challenging physical task for longer than when they said neutral words. Cursing seemed to help them feel more focused, more confident and less distracted

Nanoflowers, which look white, can help healthy cells, colored yellow, deliver mitochondria, colored red, to nearby cells. 

A New Way to Boost the Powerhouses of the Cell Might Combat Aging and Degenerative Diseases, Lab Study Suggests

Creating mini mitochondria factories helped recharge damaged cells in a dish, providing proof-of-concept work that could pave the way to new regenerative medicine therapies

In 2025, researchers watched an interstellar comet, learned about human origins and traced the spread of measles.

The Ten Most Significant Science Stories of 2025, From Medical Breakthroughs to an Interstellar Visitor

All year long, these moments captivated the public, demonstrated dangerous trends, and pushed research and innovation forward

Illustration of a T lymphocyte white blood cell, depicted in blue, attacking a cancer cell, shown in red

Scientists Engineered Cancer-Fighting Cells Inside Patients’ Bodies—and Two Early Trials Show Promise

Two recent studies show the novel therapy works in people with multiple myeloma, but researchers are trying to minimize side effects

A rinkhals (Hemachatus haemachatus) in Hluhluwe, South Africa, performs a threat display. These snakes tend to live on the edges of human communities.

The High-Stakes Quest to Make Snakebites Survivable Took Leaps Forward This Year, With Promising New Avenues to Safer Antivenoms

A wave of fresh science is challenging a century-old treatment and offering hope to the people snakebites harm most—often far from hospitals and help

Excess weight can harm a cat's quality of life and exacerbate health conditions.

Can GLP-1s Help Fat Cats Lose Weight? The First Clinical Trial Testing the Drugs for Weight Loss in Felines Has Begun

San Francisco-based pharmaceutical company OKAVA is investigating an implant that slowly releases a GLP-1 medication for up to six months

A dead tree stands with its bare, white trunk and branches in contrast to the greenery around it.

What’s Killing These Oak Trees in the Midwest? Conservationists Believe Drifting Herbicides Are to Blame

When Illinois landowners noticed tree deaths and diseases on their properties ramp up in 2017, they suspected industrial agriculture. A survey found herbicides in 90 percent of tree tissues

The Black Death may have killed more than half of Europe's population within just a few years.

A Volcanic Eruption in 1345 May Have Triggered a Chain of Events That Brought the Black Death to Europe

Ash from the explosion may have led to crop failure and famine in southern Europe, leading some Italian cities to import grain—which possibly carried fleas infected with the bubonic plague

A microscope image of HIV particles, in red, replicating from an infected cell, in blue.

A New Trial Put Immune System-Boosting Therapies to the Test to Fight HIV, Raising Hopes for Keeping the Virus at Bay

In the small study, seven out of ten participants maintained low levels of HIV for several months after receiving the experimental treatment and stopping their usual daily medications

The World Health Organization conditionally recommends the use of GLP-1 drugs, including tirzepatide, marketed as Mounjaro and Zepbound, for obesity treatment. 

Here’s What the World Health Organization Had to Say About GLP-1s in its First-Ever Guideline on the Drugs

The health agency supports the long-term use of the medications in combination with a healthy diet and exercise, and calls for equitable access to the drugs

Smithsonian magazine's picks for the best books about science in 2025 include Replaceable You, Dinner With King Tut and North to the Future.

The Best Books of 2025

The Ten Best Science Books of 2025

From “experimental archaeology” to the mysterious appeal of exploration, the wide-ranging subjects detailed in these titles captivated Smithsonian magazine’s science contributors this year

A digital illustration of an HIV-infected T cell. Once infected, the immune cell is hijacked by the virus to produce and release many new viral particles before dying. As more T cells are destroyed, the immune system is progressively weakened.

New Trials Hint That ‘Functional Cure’ for HIV May Be Within Reach, Helping Some Patients Achieve Lasting Remission

People infected with HIV must take antiretroviral drugs for life. But engineered antibodies appeared to suppress the virus for certain participants in recent trials in Africa and Europe

The National Highway Traffic Safety Administration has approved the specifications of THOR-5F, a female crash test dummy developed by Humanetics.

Will This Newly Approved Crash Test Dummy Make Car Accidents Less Deadly for Women?

The government approved the specifications of THOR-05F, marking a first step toward the government and manufacturers potentially using the dummy in future car safety tests. But it still represents only the smallest women in the United States

Oliver and his father, Ricky

This Toddler Was the First Person to Receive a Test Treatment for a Rare Genetic Disorder. Nine Months Later, His Progress Is Inspiring Hope

Oliver Chu is one of five kids participating in a clinical trial investigating a gene therapy for Hunter syndrome, a disorder with symptoms akin to childhood dementia that limits life expectancy

New research suggests multilingualism may slow cognitive aging. 

Neuroscientists Studied More Than 80,000 People and Found That Speaking Multiple Languages Might Slow Down Brain Aging

An enormous analysis of data from a broad array of participants found an association between multilingualism and cognitive aging

A team of doctors at NYU Langone transplanted a pig kidney into a brain-dead patient and reversed its rejection twice during the 61-day study.

Scientists Reverse Human Rejection of Pig Organ Transplant for First Time

A new study reversed transplant rejection twice, uncovering the reasons for transplant rejection on a cellular level

The daily pills are designed for use among those whose high cholesterol is not reaching healthy targets despite taking other medications.

New Daily Pill Could Potentially Be Life-Saving for Americans With High Cholesterol Levels, Researchers Say

The medication, which significantly lowers the risk of heart attacks, could be a promising alternative to expensive and unpopular injectables

Vincent van Gogh paintings on display at the Courtauld Gallery earlier this year

New Research

Can Visiting an Art Gallery Lower Your Stress Levels and Improve Your Health?

New research found that cortisol levels dropped among volunteers who spent 20 minutes looking at masterpieces at London’s Courtauld Gallery

Researchers found an association between moderate step counts and slower cognitive decline among people at risk of developing Alzheimer's. 

A Short Walk in the Park Might Slow Cognitive Decline in People at Risk of Developing Alzheimer’s

New research indicates that even moderate step counts, as low as 3,000 steps daily, were linked with delayed symptom onset

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