Mind & Body

Mark Prausnitz holds an experimental microneedle contraceptive skin patch. Designed to be self-administered by women for long-acting contraception, the patch could provide a new family planning option.

Will Microneedle Patches Be the Future of Birth Control?

Researchers are developing a new long-acting, self-administered device that delivers hormones beneath the skin’s surface

By genetically modifying a patient's own immune cells to target and kill cancer cells, CAR-T therapy offers a whole new way to fight cancer.

The Possibilities and Risks of Genetically Altering Immune Cells to Fight Cancer

Of the ten or so patients I’ve treated with CAR-T, over half developed strange neurologic side effects ranging from headaches to seizures

In Pursuit of Better Baby Formula

Replicating human milk is no easy feat—nor is separating the science from the hype

Unlike classic CRISPR-based editing, which fully cleaves DNA in two, prime editing starts with a cut to only one strand of the double helix.

A New Gene Editing Tool Could Make CRISPR More Precise

Prime editing offers a new way to make changes to DNA while avoiding some of the drawbacks and clunkiness of traditional CRISPR

Soldiers take a psychological test (the exact type of examination is unclear) in Camp Lee in Virginia in November 1917, the year the United States entered World War I and  Woodworth first developed his test.

The Future of Mental Health

The First Personality Test Was Developed During World War I

Long before online quizzes and Myers-Briggs, Robert Woodworth’s “Psychoneurotic Inventory” tried to assess recruits' susceptibility to shell shock

This image shows a preliminary portrait of a juvenile female Denisovan based on a skeletal profile reconstructed from ancient DNA.

Scientists Recreate the Face of a Denisovan Using DNA

By mapping gene expressions, researchers can determine some anatomical features of our distant hominin relatives

Scientists are starting to get a better idea of how many factors can influence a newborn's gut microbiome.

Babies Born by C-Section Have Different Gut Microbes Than Vaginally Delivered Infants

Method of delivery can influence the bacteria in infants' guts, according to a new study, but differences were found to disappear within nine months

Visualization of a diffusion tensor imaging (DTI) measurement of a human brain. Depicted are reconstructed fiber tracts that run through the mid-sagittal plane.

The Gut Microbiome Could Speed Up the Progression of Alzheimer’s Disease

The microbes in the gastrointestinal tract influence the immune system and the brain, possibly playing a role in the development of Alzheimer’s

In groundbreaking clinical trials, researchers are trying to treat patients by editing the genetic makeup of cells with a tool called CRISPR.

Four U.S. CRISPR Trials Editing Human DNA to Research New Treatments

Breaking down how the gene editing technology is being used, for the first time in the United States, to treat patients with severe medical conditions

Brain donation is of critical importance for scientists' understanding of brain disorders.

Inside a Brain Bank, Where Humans' Most Precious Organ Is Dissected and Studied

Unlike organ transplants, brains are used primarily to support research of some of the most widespread and debilitating diseases in the world

The team has applied for a patent for the material (shown here in a petri dish) and continues to test it at the micro- and nano-scale to better understand how it works.

How Scientists Are Using Eggshells to Grow New Bone

People with bones damaged by accidents, cancer or aging could one day benefit from bone grafts strengthened with chicken eggshells

Sarah Stewart circa 1950.

Women Who Shaped History

The Woman Who Revealed the Missing Link Between Viruses and Cancer

Today, vaccinating against cervical cancer is routine. But before Sarah Stewart, scientists dismissed the idea of a cancer-preventing vaccine as ludicrous

The microbiome—a collection of organisms including bacteria, archaea, fungi and viruses that live in the human gut—has been shown to play a significant role in brain function.

How the Gut Microbiome Could Provide a New Tool to Treat Autism

A growing body of evidence suggests the behavioral symptoms of autism spectrum disorder could be linked to bacteria in the gut

The lines scribbled over this famous Georges Seurat painting come from an experiment that tracked how the human eye jerks around as it takes in the details of the scene.

Our Eyes Are Always Darting Around, So How Come Our Vision Isn't Blurry?

Our brains manage to construct stable images even as our eyes keep jerking around. Here’s what we know about how that happens.

A digitally-colorized scanning electron micrograph depiction of a Giardia lamblia protozoan caught in a late stage of cell division, producing a heart-shaped form. Most protozoa, or singled-celled eukaryotes, reproduce asexually, but there is evidence to suggest Giardia lamblia can reproduce sexually as well.

The Evolution of Sex Could Have Provided a Defense Against Cancer Cells

The first sexually reproducing organisms may have found that the energy-intensive enterprise bolstered defenses against malignant cells

An ancient population of Arctic hunter-gatherers, known as Paleo-Eskimos, made a significant genetic contribution to populations living in Arctic North America today.

Ancient DNA Reveals Complex Story of Human Migration Between Siberia and North America

Two studies greatly increase the amount of information we have about the peoples who first populated North America—from the Arctic to the Southwest U.S.

In 1954, John Kirklin of the Mayo Clinic created the Mayo-Gibbon heart-lung machine when he modified a design pioneered by John Gibbon. The machine is now in the collection of the Smithsonian National Museum of American History.

This 1950s Heart-Lung Machine Revolutionized Cardiac Surgery

Open-heart procedures evolved rapidly once Mayo Clinic surgeon John Kirklin made his improvements to an earlier invention

Nazi officials use calipers to measure an ethnic German's nose on January 1, 1941. The Nazis developed a pseudoscientific system of facial measurement that was supposedly a way of determining racial descent.

Race in America

The Disturbing Resilience of Scientific Racism

A new book explores how racist biases continue to maintain a foothold in research today

A collection of Hominin teeth used to determine the rate of tooth evolution among human ancestors.

The Teeth of Early Neanderthals May Indicate the Species' Lineage Is Older Than Thought

Some of the oldest known Neanderthal remains include teeth that could push back the split with modern human lineages, but not all scientists are convinced

Scanning electron micrograph of HIV-1 (in green) budding from cultured lymphocyte (a type of white blood cell). Multiple round bumps on cell surface represent sites of assembly and budding of virions.

Scientists Identify Factors That Make People Naturally Resistant to H.I.V.

Studying key points on the H.I.V. virus that are weak to immune system attacks could lead to new treatments or H.I.V. vaccines

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