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Science / Mind & Body

The Polar Bear Swim in Vancouver in 1978. Lisa Pantages, second from the left, will complete her 64th annual plunge this New Year’s.

‘Excitement With a Little Dash of Fear’: Polar Plunges Ring in the New Year With a Splash. But What Actually Happens to Your Body?

Three experts share the science behind taking a dip in cold water—and offer safety tips that any potential plungers should bear in mind

In 2025, researchers watched an interstellar comet, learned about human origins and traced the spread of measles.

The Ten Most Significant Science Stories of 2025, From Medical Breakthroughs to an Interstellar Visitor

All year long, these moments captivated the public, demonstrated dangerous trends, and pushed research and innovation forward

A rinkhals (Hemachatus haemachatus) in Hluhluwe, South Africa, performs a threat display. These snakes tend to live on the edges of human communities.

The High-Stakes Quest to Make Snakebites Survivable Took Leaps Forward This Year, With Promising New Avenues to Safer Antivenoms

A wave of fresh science is challenging a century-old treatment and offering hope to the people snakebites harm most—often far from hospitals and help

Smithsonian magazine's picks for the best books about science in 2025 include Replaceable You, Dinner With King Tut and North to the Future.

The Best Books of 2025

The Ten Best Science Books of 2025

From “experimental archaeology” to the mysterious appeal of exploration, the wide-ranging subjects detailed in these titles captivated Smithsonian magazine’s science contributors this year

A digital illustration of an HIV-infected T cell. Once infected, the immune cell is hijacked by the virus to produce and release many new viral particles before dying. As more T cells are destroyed, the immune system is progressively weakened.

New Trials Hint That ‘Functional Cure’ for HIV May Be Within Reach, Helping Some Patients Achieve Lasting Remission

People infected with HIV must take antiretroviral drugs for life. But engineered antibodies appeared to suppress the virus for certain participants in recent trials in Africa and Europe

Students learn anatomy from an Asclepius AI Table, which merges interactive elements and artificial intelligence.

Medical Students Are Learning Anatomy From Digital Cadavers. Can Technology Ever Replace Real Human Bodies?

From interactive diagrams to A.I. assistants, virtual tools are beginning to supplant physical dissections in some classrooms

New research strives to understand what happens in the brain at the transitions between sleeping and being awake.

At the Mysterious Boundary Between Waking Life and Sleep, What Happens in the Brain?

Neuroscientists studying the shifts between sleep and awareness are finding many liminal states, which could help explain the disorders that can result when sleep transitions go wrong

Hyper-realistic reconstructions of Australopithecus afarensis (Lucy foreground, Selam background) by Élisabeth Daynès in the National Museum’s “People and Their Ancestors” exhibition, Prague

Meeting Lucy: How a World-First European Exhibition Brought Visitors Face to Face With the Fossil That ‘Shrinks Time’

Two Australopithecus fossils named Lucy and Selam made a rare trip out of Ethiopia for a 60-day display at the National Museum in Prague

Horseshoe crabs evolved 445 million years ago and have been around for 1,500 times longer than Homo sapiens. It was not until the 20th century, however, that scientists discovered life-saving properties in their blood.

Horseshoe Crab Blood Has Long Helped Us Make Safe Medicines. Now, Alternatives That Spare the Ancient Creatures Might Be Breaking Through

An enzyme in the blue blood has been key to testing vaccines since the 1980s, raising concerns for the crabs’ population. But regulatory approval and new data are signaling the tide may be turning

Postpartum depression affects some one in eight women in the United States. It typically occurs in the first weeks after childbirth, after a sudden drop in levels of estrogen and progesterone.

A Blood Test Can Now Predict a Mother’s Risk of Postpartum Depression

Scientists are learning more about this leading complication of childbirth, and treatments are improving

People with a rare form of epilepsy have reported feelings of bliss just before having a seizure. A French Swiss neurologist has pinned down where this “aura” originates in the brain in hopes that one day, that feeling might be reproduced non-invasively in others.

Some People Experience Blissful Ecstasy Right Before a Seizure. Could Understanding This Feeling Help Treat Depression?

A neurologist shares her thoughts and research about “ecstatic epilepsy” in a wide-ranging conversation on how we perceive the world—and create the world we perceive

The patient looks through measuring goggles at a series of markers on a grid. 

Can a Medical Device Restore Your Balance?

Nearly two million people worldwide have lost the simple ability to feel steady. Now researchers have developed an experimental medical implant that promises to restore the sensory machinery responsible for balance

Heart disease is the leading cause of death globally, according to the World Health Organization.

This 14-Year-Old Built an App That Detects Heart Diseases in Seconds

Siddarth Nandyala wants to put his tool in the hands of medical professionals so that they can catch cardiovascular abnormalities in their early stages

New research is revealing how climate change is impacting our eyes.

Climate Change Is Threatening Eye Health in Disturbing Ways

Cataracts, pinkeye and other ocular disorders are linked to heat, air pollution and higher UV exposure

Blood type, metabolism, exercise, shirt color and even drinking beer can make individuals especially delicious to mosquitoes.

Ask Smithsonian

Why Do Mosquitos Bite Some People More Than Others? Your Blood Type, Sweat Contents and Even Alcohol Consumption May Make You More Attractive to the Pesky Insects

Scientists are working hard to discover the factors that drive the blood-sucking insects to target certain individuals

Psychiatric neurosurgery, originally known as psychosurgery, involves operating on the brain to alter its function.

What Does the Future Hold for Psychiatric Brain Surgery?

For some patients, removing brain tissue can help treat OCD and other disorders. But ethical concerns remain

Chloe Yehwon Lee was a finalist in the 2025 Regeneron Science Talent Search, the most distinguished STEM competition for high school seniors in the United States.

This 17-Year-Old Scientist Is Making an Acetaminophen Alternative That Is Less Damaging to the Liver

Chloe Yehwon Lee’s research could change the painkiller, known by the brand name Tylenol, for the better, ultimately reducing emergency room visits and cases of liver failure

More than a third of endometriosis patients are misdiagnosed with mental health conditions.

For Some Women With Serious Physical Ailments, Mental Illness Has Become a Scapegoat Diagnosis

Patients with difficult-to-diagnose conditions like endometriosis are often sent home with diagnoses like anxiety or bipolar disorder

The city of Potosí rests at high altitude in Bolivia.

Can Researchers Find Remedies for the Problems Created by High-Altitude Pregnancies?

In people not adapted to life at altitude, the sparse oxygen can impair fetal growth, causing issues that can last a lifetime

During conversations, interjections act as vital traffic signals.

Huh? Interjections Are Critically Important to Communication

Utterances like “um,” “wow” and “mm-hmm” aren’t garbage—they keep conversations flowing

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